LOSEC - a patient's guide
DRUG NAME: omeprazole
Losec is used for the treatment of stomach ulcers, gastro-oesophageal reflux disease (GORD) and Zollinger-Ellison syndrome (A rare condition with very high stomach acid). It is also prescribed for NSAID-associated (e.g. aspirin) ulceration, and during general anaesthesia to prevent acid aspiration.
This medicine is known as a proton pump inhibitor which blocks excess stomach acid production via a unique mechanism ( H+,K+-ATPase). By controlling the production of excess acid it allows the eroded lining of the stomach or oesophagus to heal due to the agent's long duration of action and high potency.
- Gastric cancer
- Liver disease
- Pregnancy and breastfeeding
- headache, dizziness
- stomach upset/pain
- blurred vision
- dry mouth
- muscle and joint pain
This medicine inhibits the metabolism of diazepam, phenytoin, warfarin (monitor).
- Follow instructions carefully on the label of this medicine or as directed by your doctor.
- Take this medicine regularly for it to work effectively (approximately 4 days until maximum effect).
- Avoid smoking and eating certain foods (talk to your pharmacist).
- Food: Taken after if this medicine upsets your stomach
- Alcohol: May aggravate ulcer so best avoided
- Swallow capsule whole or open capsule and mix contents with fruit juice or yoghurt.
- Contact your doctor or seek urgent medical help if side effects are severe or ongoing.